GRM1 and schizophrenia: However, the reported findings of altered mGluR1 expression in post-mortem schizophrenia brains and the clinical success of a group II mGluR agonist in the treatment of schizophrenia suggest a potentially important role of mGluRs in schizophrenia (Patil et al., 2007; Volk et al., 2010).