MAOA and Anxiety: Several lines of evidence have shown that MAO-A inhibitors reduce anxiety and neophobia (Caille et al., 1996; de Angelis, 1996; Eroglu and Guven, 1998; Steckler et al., 2001); furthermore, the antidepressant effects of these drugs have been shown to reflect their ability to increase the resilience to acute stress (Miura et al., 1996; Ferigolo et al., 1998; Cryan et al., 2005).