Additionally, A20 mRNA expression analysis of selected cases (6 MM cases with monoallelic A20 deletion and 14 MM cases without monoallelic A20 deletions) demonstrating a significant correlation between the presence of monoallelic A20 deletions (Spearman rho = -0.704, p<0.01) and the IRS of A20 IHC analysis (Spearman rho = 0.86, p<0.01, Fig 3). The gene discussed is TNFAIP3; the disease is Miyoshi myopathy.