Two of the 7 NF-κB target genes—namely BCL2 and CCR7- were at least 17 fold higher expressed in MM cases with and without A20 deletion (p<0.02, Fig 3) whereas Cyclin D1 and CD44 were at least 35 fold higher expressed in MM cases with A20 deletions (p<0.01, Fig 3) compared to BM. Here, TNFAIP3 is linked to Miyoshi myopathy.