Some studies revealed that IL-8 had a higher expression in melanoma, glioblastoma, non-small-cell lung carcinoma, and colorectal cancer, and through binding to G protein-coupled receptor CXCR1 and CXCR2, it was closely linked with angiogenesis, tumor growth, metastasis and survival[8–11]. This evidence concerns the gene CXCL8 and neoplasm.