NF-κB overexpression and constitutive activation has already been reported in several tumour types, including CC, lymphoma, leukemia, breast cancer, pancreatic adenocarcinoma and gastric carcinoma.26 In addition, tumours with increased NF-κB activity present higher resistance to treatment.27, 28 In the present work, we confirmed the aberrant expression and activation of NF-κB in CC. Here, NFKB1 is linked to pancreatic adenocarcinoma.