Dominant negative effects on the plasma membrane trafficking have also been seen in other potassium channelopathies, such as long QT syndrome type 1 and 2, nonsyndromic sensorineural deafness type 2 and SCA13, which are disorders caused by truncating and missense mutations in other voltage-gated potassium channels Kv7.1, Kv11.1, Kv7.4 and Kv3.3, respectively [41–44]. Here, KCNQ4 is linked to long QT syndrome 1.