As HSF1 has been described to regulate the transcription of the NK cell ligands MICA and MICB [12, 13], we investigated whether treatment of tumor cells with NZ28 and/or NVP-AUY922 alters the cell surface density [mean fluorescence intensity (MFI)] of the NK cell ligands MICA and MICB on tumor cells. This evidence concerns the gene HSF1 and neoplasm.