IL6 and obesity due to melanocortin 4 receptor deficiency: For IL-6 a similar pattern was observed however obesity appeared to dampen the impact of exercise on IL-6 mRNA in offspring of obese dams (CE 2.5±0.5 vs CS 0.87±0.2; FE 1.58±0.3 vs FS 0.87±0.1, P<0.05).