We found that MS susceptibility loci are substantially enriched for both EBNA2 (O/E calculated for MS regions, MHC removed = 5.392-fold, p < 2.0e-05; MHC included = 5.047-fold, p < 2.0e-05) and RBPJ (O/E calculated for MS regions, MHC removed = 6.841-fold, p < 2.0e-05; MHC included = 6.402-fold, p < 2.0e-05) (Table 1). Here, RBPJ is linked to myeloid sarcoma.