FGF2 and ischemia: For example, changes in stress-induced ischemia and myocardial perfusion were assessed by treadmill exercise testing and dual-isotope gated SPECT thallium-201/99mTc-sestamibi perfusion SPECT imaging at baseline, day 29, day 57 and day 180 after administration of the pro-angiogenic recombinant-fibroblast growth factor 2 (rFGF2) in a clinical study [9].