Moreover, triggering of the TCR induces expression of the glutamine transporter ASCT2 in T cells and the deletion of ASCT2 suppressed the development of pro-inflammatory CD4 helper 1 (Th1) and Th17 cells in vivo in mouse models of autoimmunity highlighting the integration of T cell responses to antigen with changes in T cell glutamine metabolism (7). The gene discussed is SLC1A5; the disease is Autoimmunity.