We focused on the single nucleotide polymorphism (SNP) rs11174811 on the AVPR1a gene (located on chromosome 12q), because not only has it been associated with phenotypes related to anxiety/negative emotionality [e.g., stress reactivity, drug addiction, blood pressure, partnership satisfaction, and aggressive behavior (Maher et al., 2011; Nossent et al., 2011; Levran et al., 2014; Malik et al., 2014)], but also the functionality of this gene variant has been demonstrated by means of mRNA expression in postmortem brain tissue. Here, AVPR1A is linked to Anxiety.