As we detected additional high intensities of UBB+1 immunoreactivity, especially in five other brain areas in line 3413, we focus here on these brain areas known to be affected in AD, namely the olfactory bulb (OB), basal ganglia, nucleus basalis of Meynert (NBM), raphe nuclei and inferior colliculus (IC) and discuss their potential relevance for AD research. The gene discussed is UBB; the disease is Alzheimer disease.