SLC6A4 and obsessive-compulsive disorder: Animal models of maternal immune activation using the viral mimic polyI:C report similar reductions, but not elimination, of sociability.21, 33 Offspring of MAA dams also exhibited increased marble-burying behavior, a perseverative behavior analogous to repetitive behaviors observed in neuropsychiatric disorders including obsessive compulsive disorder and ASD.43 In addition, we observed disturbances in the serotonin pathway with increased SERT evident in offspring of MAA-exposed dams.