Neither TGF-β1 or TGF-β2 gene nor TGF-β target gene expression differed by NF1 mutation status, irrespective of whether all glioblastomas pooled or only mesenchymal tumors were analyzed, with the exception of PAI-1, which was increased in patients with NF1 mutations for all patients pooled (p=0.048), but not for the subgroup of mesenchymal tumors (p=0.663) (Supplementary Figure 9B). Here, NF1 is linked to mesenchymal cell neoplasm.