In the subgroup of recurrent glioblastomas, significant correlation of mRNA data was found between TGF-β1 and PDGF-B (r=0.62, p=0.011) or PAI-1 (r=0.54, p=0.033), but not between TGF-β2 and PDGF-B (r=0.32, p=0.226) or PAI-1 (r=0.31, p=0.226) or TGF-β3 and PDGF-B (r=0.46, p=0.072) or PAI-1 (r=0.32, p=0.226) (Supplementary Figure 5C, D, Supplementary Table 3). The gene discussed is SERPINE1; the disease is glioblastoma.