Like healthy humans, WT mice are able to clear the infection fully within 5 days of exposure to C. albicans. Although immunosuppression with corticosteroids is often used as a positive control in this model of OPC, we instead employed IL-17RA-/- mice as controls (without additional immunosuppression), since these mice are reproducibly susceptible to disease, judged by both fungal burden and progressive weight loss [6, 8]. Here, IL17RA is linked to infection.