Recent evidence has shown that IDH1 mutant diffuse gliomas and glioblastomas demonstrate unique radiological features that correlated with outcome.[5, 6] Specifically, a study examining diffuse gliomas demonstrated that IDH1 mutant tumours were smaller and less infiltrative.[6] In contrast, a study examining glioblastoma found that IDH1 mutant tumours were more likely to be non-CE, larger, and in the frontal lobe.[5] To date there have been no similar studies focusing on patients diagnosed with AA despite the wide variability in outcome among patients with this tumour. The gene discussed is IDH1; the disease is neoplasm.