MBTPS1 and T-cell large granular lymphocyte leukemia: The succession diagram in Fig 4 suggests a simple picture for the cell fate determination process: the activation of any of the three S1P-related motifs is enough to drive the system to either apoptosis (either the teal or the green stable motif in Figs. 3 and 4) or T-LGL leukemia (the red stable motif in Figs. 3 and 4).