Given that both EtOH and TORKinibs inhibit mTOR signaling, we attempted to systematically compare the effect of EtOH and INK128 on mTOR signal transduction and interaction between components of the mTORC1/2 complexes in diffuse large B-cell lymphoma (DLBCL) malignancy. This evidence concerns the gene MTOR and diffuse large B-cell lymphoma.