Attempting to address the role of IL-10 in exacerbation of infection induced by nucleosides, we measured production of IL-10 in culture supernatant of total cells from draining LNs of C57BL/6 co-inoculated with parasites plus ADO+AMP or PBS and re-stimulated them in vitro with soluble Leishmania Ag (SLA). Here, IL10 is linked to infection.