Two independent SNPs in IL12B (r2 = 0.20) showed associations with ER-negative disease after chemotherapy: rs2546892 (G > A) with poorer OS (HR 1.50 (95% CI 1.21, 1.86), P = 1.81 × 10−4), and rs2853694 (A > C) with improved OS (HR 0.73 (95% CI 0.61, 0.87), P = 3.67 × 10−4). The gene discussed is IL12B; the disease is glycogen storage disease VI.