GRK2 and pancreatic neoplasm: Of interest, Panc-1 and S2-007 cells, which had been used for the parallelized functional assays with recombinant expression of fluorescence-tagged candidate genes, showed no detectable endogeneous ADRBK1 expression, while the majority of pancreatic cancer cell lines expressed moderate or high levels of ADRBK1 mRNA (Fig 5C).