In line with previous reports [22-24], human transformed and tumor cell lines, MCF-10A neoT and U-87 MG, had higher levels of intracellular and plasma membrane bound CatB than non-tumor vascular endothelial cell lines (p<0.001 and p<0.05, respectively) (Table 1 and Fig. 1A). This evidence concerns the gene TYRP1 and neoplasm.