KCNN4 and neoplasm: This view is in line with the channel’s role in driving tumor cell and tumor invasiveness, as outlined above, as well as in endothelial cell proliferation, as concluded from pharmacological in-vitro and in-vivo studies testing anti-proliferative actions of KCa3.1 blockers like TRAM-34 on endothelial cell proliferation and artificial matrigel-vascularization [20].