HSPA4 and cancer: Even unlabeled proteomic analysis of unstressed cancer cells for example can provide rather precise quantities for a few hundreds proteins, such as HSPs and metabolic enzymes, that could serve for diagnostic purposes, as in the case of particularly resistant cancer cells displaying abnormally high levels of HSP70 and high levels of metabolic enzymes involved in glycolysis (Finka and Goloubinoff 2013).