In our study, we analyzed the protein and mRNA expression of CADM1 in various cervical cancer cell lines, including C33A (HPV-negative), HeLa (HPV18 positive), and SiHa and CaSki (HPV16-positive) cells, and found that CADM1 was significantly downregulated in three HPV-induced cervical cell lines. Here, CADM1 is linked to cervical carcinoma.