MYC and esophageal squamous cell carcinoma: To determine the mechanism of miR-942 upregulation in ESCC, the miR-942 promoter region was analysed using the UCSC genome browser (http://genome.ucsc.edu/), and two binding sites for c-myc (E-box1 and E-box2) were predicted on the promoter of miR-942 (Fig. 6A).