In foreskin fibroblasts and ectocervical tissue, ligands for TLR3 (poly I:C) and TLR4 (LPS) inhibited the HCMV infection, inducing the secretion of interleukin 8 (IL-8) and IFN-ß (12). The gene discussed is CXCL8; the disease is cytomegalovirus infection.