Our present study demonstrated that human astrocytoma cells U87 can produce and release to the extracellular space constitutive amounts of NGF and BDNF protein in accordance with the observations of van Wagoner et al. (1999), Mori et al. (2008), Angelucci et al. (2011) and Mele and Jurič (2014). This evidence concerns the gene NGF and astrocytoma (excluding glioblastoma).