miR-199a-3p is significantly down-regulated in ovarian cancer and its restoration has been reported to be linked with the inhibition of PAK4, CD44, and mTOR [14, 15, and 16], all of which are related to cancer progression, indicating that miR-199a-3p might have multi-tumor suppressor functions at least in ovarian cancer. This evidence concerns the gene PAK4 and ovarian carcinoma.