ANO1 and metastatic malignant neoplasm in the lymph nodes: Although TMEM16A amplification was significantly correlated with overexpression (p = 0.021, Phi = 0.120) (Table S1), TNM stage (p = 0.001) and lymph node metastasis (p = 0.023) (Table S2), it failed to be a prognostic factor of overall survival of patients with GC (p = 0.557) (Fig. S1).