Additionally, 42% (27/65) of tissue samples removed from breast cancer patients had CYP26A1 overexpression; CYP26A1 overexpression may induce intracellular RA consumption, thus pushing the cells toward tumorigenicity; CYP26A1 may be recommended as a candidate oncogene [41]. The gene discussed is CYP26A1; the disease is breast carcinoma.