IRF1 and neoplasm: Continuing with the qPCR analysis, we first confirmed the changes presented in Figure 3A (results not shown) and then showed that the genes encoding aurora kinase A (Aurka) and the germinal center B cell master transcription factor Blimp-1 (Prdm1) were up-regulated in tumor cells, whereas expression of Irf1 (interferon regulatory factor 1, Egr1 (early growth response 1) and Bcl2 (B cell leukemia 2) was decreased (Figure 3B).