TP53 and neoplasm: qPCR analysis of RNA from tumor cells isolated from seven different IL-6- and/or MYC-induced neoplasms included in Figure 2A and B demonstrated that three well-established NF-κB target genes were consistently up-regulated in this sample: Cdkn1a, a target of the tumor-suppressor p53, and two DNA repair genes, Fancd2 and Xcrcc6 (Figure 3A).