Recent studies report that GM-CSF is critical for the pathogenicity of Th17 cells [3, 4] and the presence of Th1/17 cells was observed at the inflammatory site of inflammatory bowel disease (IBD), multiple sclerosis (MS), and juvenile idiopathic arthritis (JIA) [76, 78, 81, 82]. This evidence concerns the gene CSF2 and myeloid sarcoma.