Among postmenopausal group multivariate logistic regression analysis, with the risk for BC as the dependent variable and adiponectin, leptin, resistin and visfatin, BMI, WC, TG, TC, HDLc, LDLc, and glucose as independent variables, showed that the variables including BMI, TG, adiponectin, leptin, visfatin, and resistin were accepted by the final model. This evidence concerns the gene LEP and breast cancer.