IFNG and rheumatoid arthritis: Of note, a similar reduction in release of the signature Th1 cytokine IFNγ was exhibited when 11a was tested in CIA (Al-Riyami et al., 2013) and when peripheral blood mononuclear cells and synovial fluid membrane cultures from human patients with RA were pre-exposed to ES-62 (Harnett et al., 2008).