Onofri et al. [8, 9] showed that ligands of VEGF receptors influence angiogenesis in pituitary adenomas and affect growth of pituitary tumor cells through VEGFR-1, and that VEGF and VEGFR-3 immunostaining in pituitary tumors was higher than in normal pituitary tissue. Here, FLT4 is linked to pituitary gland adenoma.