CEACAM1, CEACAM5 and CEACAM6 may be released from epithelial tumors in microvesicles, whereas tumor endothelia only contain CEACAM1 which has a receptor function for other CEACAMs, influences T cell behavior [17] and regulates the tumor matrix and microvascularization [18]. The gene discussed is CEACAM5; the disease is neoplasm.