There are no large tumor series from BRCA1/2 mutation carriers that allow gene expression interactions in these mutation backgrounds to be assessed; therefore our analysis was restricted to sporadic cases and aimed to explore complex relationships between HMMR and AURKA or TUBG1. Using the NKI-295 dataset [22], HMMR expression was found to be significantly associated with overall survival: two microarray probes gave identical results: HR = 1.78 and p = 0.001. This evidence concerns the gene AURKA and neoplasm.