ESR1 and neoplasm: Finally, the analysis of rs2426618 by ERα tumor status in BRCA2 mutation carriers did not reveal specific associations: ERα-positive, per-allele HR = 1.10, 95% CI 1.02–1.17, p = 0.010; ERα-negative, per-allele HR = 1.11,95% CI 0.97–1.26, p = 0.15, pdifference = 0.89.