STC2 and breast cancer: We found that fewer 231 STC2 cells migrated through the membrane in the migration chamber than did 231 vector cells (Fig. 3A-B), which was also confirmed in two more breast cancer cell lines MCF-7 and ZR-75-30 by overexpressing STC2 (Fig. 3E-F), but more 231 HM STC2i cells migrated through the membrane than did 231 HM Scr cells (Fig. 3A-B).