Co-localization studies showed that the intracellular Tn-positive structures in HSV-1-infected cells were highly correlated with the Golgi marker giantin during early stages of infection (Fig 4A: HSV-1 5 hpi), whereas lower degree of co-localization was observed late in infection (Fig 4A: HSV-1 9 hpi). Here, GOLGB1 is linked to infection.