Finally, geshoidin, previously reported to inhibit glutathione transferases [24], and1-(3-acetyl-2,4-dihydroxy-6-((3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)oxy)phenyl)-4,5-dihydroxy-2-methylanthracene-9,10-dione (2MA), which is structurally similar to compounds reported with tumor cytotoxic activity [25], also did not inhibit HIV-1 in our assay. Here, HPGDS is linked to neoplasm.