PFKP and nonpapillary renal cell carcinoma: Phosphofructokinase, platelet (PFKP, Gene ID: 5214; mRNA increased 10-fold in TRACK mice and 7-fold in ccRCC) encodes a kinase enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate during the third step of glycolysis.