USF1 and glioma: In this study, we identified the following: LMO3 is increased in glioma cell lines and tissues and is correlated with a poor prognosis; miR-101 induces apoptosis by suppressing LMO3; and miR-101 inhibits the expression of LMO3 by recovering its methylation status via the regulaton of methylated histone occupation and the suppression of the transcription factors USF and MZF1 in gliomas.