IFNL3 and coinfection: In multivariate analyses, variables associated with RVR were: LVL [Odds Ratio:4.54 (95%CI: 2.47–8.34); p < 0.001], HIV co-infection [OR: 0.45(95%CI: 0.22–0.91); p = 0.027], IL28B-CC [OR: 7.81 (95%CI:4.29–14.38); p < 0.001], Genotype 1 [OR: 0.42 (95%CI:0.21–0.81); p = 0.01], Forns’ Index [OR: 0.71 (95%CI:0.60–0.83); p < 0.001] (Table 3).