SLC12A5 and schizophrenia: In both the DLPFC and the ACC, subjects with schizophrenia off antipsychotics for 6 weeks or more at the time of death had a 38% and 35% decrease in KCC2 expression compared to subjects with schizophrenia on antipsychotics, respectively [F(1,30) = 2.159, p<0.05 and F(1,31) = 2.439, p<0.05] (Fig 2E and 2F).