Moreover, our data showed that TT genotype in rs11871275 of ACACA gene reduced the recurrence risk of HCC when compared to patients with AA and AT genotypes (HR = 0.41, 95% CI = 0.17–1.00; P = 0.05), whereas variant genotype (GC/CC) in rs4485435 of FASN gene was associated with increased recurrence risk, when compared to patients with GG genotype (HR = 1.32; 95% CI = 1.02–1.72, P = 0.03). The gene discussed is FASN; the disease is hepatocellular carcinoma.