In addition to LLC cells, we also demonstrated that TGFβ1-mediated cell growth suppression was enhanced by LRG in human hepatoma Hep3B cells, which have been reported to be sensitive to TGFβ1-mediated cell growth suppression, resulting in apoptosis (Fig. 6) [20, 25]. Here, TGFB1 is linked to hepatocellular carcinoma.