We also used Kaplan-Meier and Cox regression models to examine whether pBcl-2-S87 expression in tumors from 190 colorectal cancer patients could be associated with PXN, Bcl-2, and MMP2 expression and whether pBcl-2-S87 expression had a prognostic significance regarding overall survival (OS) and relapse free survival (RFS) in these patients. The gene discussed is PXN; the disease is colorectal cancer.