Serum FSIP1 level in the 112 patients with recurrent or metastatic breast cancer was also much higher than those of the patients with primary breast cancer (7, 713 ± 3, 065 pg/ml vs. 4, 713 ± 3, 065 pg/ml, p = 0.003; Figure 2A). The gene discussed is FSIP1; the disease is breast carcinoma.